Repbase Reports |
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2004, Volume 4, Issue 2 |
February 29, 2004 |
Copyright © 2001-2016 - Genetic Information Research Institute |
ISSN# 1534-830X |
Page 40 |
L1-2_CR |
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L1-2_CR is a L1-like non-LTR retrotransposon - a consensus. |
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Submitted: 29-Feb-2004 |
Accepted: 29-Feb-2004 |
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Key Words: non-LTR retrotransposon; endonuclease; reverse transcriptase; L1 superfamily; L1-2_CR |
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Source: consensus |
Organism: Chlamydomonas reinhardtii |
Taxonomy: Eukaryota; Plantae; Thallobionta; Chlorophycota; Chlorophyceae; Volvocales; Chlamydomonadaceae |
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[2] |
Authors: Kapitonov,V.V. and Jurka,J. |
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Title: L1-2_CR, a family of L1-like non-LTR retrotransposons from the green algae genome. |
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Journal: Repbase Reports 4:(2) p. 40 (2004) |
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Abstract: Several hundred copies of L1-2_CR are present in the C. reinhardtii genome. They are ~98% identical to the consensus sequence and constitute ~0.5% of the genome. Since some elements are identical to each other, the genome harbors currently active L1-2_CR elements. The consensus is incomplete at the 5' end. The reconstructed portion encodes the 1439-aa L1-2_CRp protein (pos. 639-4955) composed of the endonuclease and reverse transcriptase domains. L1-2_CRp: MRRPKQAAPGPRPLRVGSHNVRGLRKRVPHLGCSRLHALLSCWERQRLDVVCLQETHVLDSDIDLVTADL AAAAQRLHAREWTAWWAPAQKPEGRRVTGGTAILIRSSLLQQGAMVLAGGAAAVSVAAGAWAGRGVSLQL QWGGHTFTLTSAYFPLASTAQQAFIREWVGLRASGSGEHLLAADFNFVADVALDTVTGRARSDGPAAAAL AAACPGLIDVLRRRHPARRVCTFFHPHGASRLDRILCSGGLEPQVLECGVAAGVPSDHMLVTVALAASPE AAPPARSLPRAHLGFRDFKDLDRDYRAWLGTALAARPTDPVELLEWWPALKRAAATSANRLSREAVTRRV AASQREAAALEAAAAAAAAVEAGGDVQVAAQAAVRARCTAAEAAVAAAAGAARRTRHAWLRGGEKPCPLL TRMLRPAGGPRVIAKLKQPDGTTTSDPTVMGQVMARYWRDVSAAPPPAPDARTQVLDALQQHGRRCTAEE ADQLGRVAVSAAEVRAALAAAPAGRAAGPDGIPVELYQHYDSDFAPVLADVFTAVGEGAGVPDGLLDGVW SFFFKSGDPTEPSNYRPITLTDTDYRTLARVLCLRLQPVFGRVIDPEQTAFLTDRRIADNVLLLQLTPGL LKAAKKAPAVAAFLDFYKAYDTVDRSFLLACLERMGVGAGFLTWVSRLLTDTRGAALVNGRVSGWVPLMA GVRQGCPLAPLLYLAVAQALLSWLRSRGHGVLANLASVLASQYADDCTPFLEGFQAVPGFLADMDVFRRA SGQRLNMTKVELMVMGTVGGAGALPAGMAGPPLPPGWRVVPAAKSLGVHYGDWGACSPPVTFEAVMGVLS KIARMPVSMFGRAAAASAYALGKVLYHLEFAGLPQLYVVDRLLARVAAVVDRRLSPAQFDANPHARPAGL SIELMQLPPAVGGAGLLPLVPHVKARQAGLAVRCVLGVCGLLPYVPPWTRVAAAWLRQVHPAATPLRLLV RGAADRVLNKPLTPAGKPFARLLKAMTALPAVTLVAPPEPGAWVSHVPLWANPALCEDGRTWEVAFADLF ALPGLACVGQLVAAHDGLNELRQALTRPWAEGSRSGEACADMYVTAVWRRVLHWSTRARLPSPLPGPASP QEAADRFAAAVALLPAGWAAAARAAQLARGPAAALPLPVADVVSATAESVQRVVRGLGWLQCGGPPILLT AYTVKAGTVLQMAPQLAALKAKHLQYVCDAGVSGVGAALAAGAFVCTLARLWSLKWENHHKEALWRVAAN ACWAFPRHASERARGVTVDPCWACGVDMQDGDRRHWFWDCTVALSLRESMGMAMGFLPEEALSAFSREEL WLVRPPAGLAPPVWDVVCLAAMSALDFGRQRVVMAGLAARAKLPSARVLSIGLAVVADFWGRLQTFVTLG IRPKGWDAVPFAHPFISRAVGDGMVLRLPYDADSPPPSP A subset of more than ten L1-2_CR elements is characterized by a remarkable target site specificity. They are inserted in different copies of the DNA-2-7_CR transposon at the same site (position 593 in the DNA-2-7_CR consensus sequence; usually the 593-601 region of DNA-2-7_CR is duplicated around the L1-2_CR inserts). The DNA-2-7_CR sequences that harbor the L1-2_CR elements are less identical to each other than the L1-2_CR sequences. Therefore, the L1-2_CR and DNA-2-7 elements cannot be different parts of the same composite transposon.
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Derived: [2] (Consensus) |
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Download Sequence - Format: IG, EMBL, FASTA |
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References:
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