Repbase Reports |
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2003, Volume 3, Issue 2 |
February 28, 2003 |
Copyright © 2001-2016 - Genetic Information Research Institute |
ISSN# 1534-830X |
Page 13 |
CR1-1a_AG |
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CR1-1a_AG is a CR1-like non-LTR retrotransposon - a consensus sequence. |
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Submitted: 28-Feb-2003 |
Accepted: 28-Feb-2003 |
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Key Words: non-LTR retrotransposon; CR1 clade; DNA/RNA-binding; endonuclease; reverse transcriptase; CR1-1_AG; CR1-1a_AG |
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Source: consensus |
Organism: Anopheles gambiae str. PEST |
Taxonomy: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Anopheles |
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[1] |
Authors: Kapitonov,V.V. and Jurka,J. |
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Title: CR1-1a_AG, a subfamily of CR1-like non-LTR retrotransposons from African malaria mosquito. |
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Journal: Repbase Reports 3:(2) p. 13 (2003) |
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Abstract: CR1-1a_AG is a subfamily of CR1-1_AG non-LTR retrotransposons. The CR1-1a_AG consensus sequence was reconstructed based on multiple alignment of ~10 copies identified in the sequenced portion of the genome. Given the ~2% divergence of these copies from the consensus sequence, transposition of CR1-1a_AG occurred less than 1 million years ago. The CR1-1a_AG and CR1-1_AG consensus sequences are 79% identical to each other. The 3' terminus of CR1-1a_AG is composed of the CAT microsatellite. CR1-1a_AG encodes two proteins: a 444-aa CR1-1a_AG-ORF1p (positions 441-1772) and 932-aa CR1-1a_AG-ORF2p (positions 1776-4571). CR1-1a_AG_ORF1p is DNA/RNA binding protein composed of the PDH domain (positions 3-38) and gag-like zinc knuckle regions (aa positions 340-444). CR1-1a_AG-ORF2p is composed of the AP endonuclease and reverse transcriptase domains. CR1-1a_AG-ORF1p: MECLACSAVVLINDDPILCAGKCGGNFHRRCVTPSLSKTAAKIINENKNVLYMCDRCLEHKSGLAGMDVD VSGSYDLLTQSIKNLESNVSVWISSALEKGIETLKTELCAQVERKLEQTLRESLSAVECSNKAKEALRAT FDDTKARETVEDESWATVTKKRKRTNSGNSNVQTIINRFDTGNVNSTPKISDKVTGPILANKNKNSKTLV IVPKVGQSCDKTRADLRAKLDPRKQQVSEFRNGKDGQVFVQCSAQVKLDELRKEVENILGDEYATDLPLS RVKIIGMSEKYTDSHLVDLLKSQNEGIPWKQVKVIGMFENKIYKYQKYNAVLEIDYESDLCLAKLGKINV GFDRCKISKSVHVMRCYGCGQFNHKSTECKNKQACSKCGDEHKTSECTSSSLKCVNCVLANSVRNLKLDV RHAANDYNCPMFKKQIERRMQLSQ CR1-1a_AG-ORF2p: QVGEELGRFREILYFNVAGLSSNYAMFRETVEKVQPLLVLISETHVIEEEAFQQFHINGYRVVSCLSHSR HTGGVAVYARSEIVLKVIFNESLEGNWFLGVAVSKGMTAGNYGILYHSPSASDSRFVDILEEWLDRFLNF SKLNIIVGDFNIDWLNVEKSAKLKSLMDSVNMKQKVNEFTRIARQSRTLIDQVYSSTDSIKVTTDPLLKI SDHETLVLNINVKRCETIQRKFKCWNRYSKFALCNHVSQGLRQEAPSFNEAADLLWNTLKKAMGTLVEEK TILSRETSRWYTLELSRAKRKRDEAYQHFIRSNSGYDWTEYTRLRNTYSRNLKTTRRNYFSGEISKHKGN SKELWKVLKSLLRPEESRVSVVKFDGLVESEDSIICQKFNLFFVNSVLDINQNIADARAPDSLFCNDAPG NQFKFQKITKEKLKTICFSLSKTAGIGNVNCNTIQDCFHVVGESLLIVINQSLEEGIFPETWKESLVIPI PKVSGAASAEEFRPINMLHVLEKVLELVVKEQLVQFLTRNDLLISEQSGYRQGHSCETALNLVLARWKVL MDRKESIVAVFLDLKRAFETISRPLLLQTLRRFGIVGKELNWFENYLKDRTQRTVFGNSISEPIENTLGV PQGSVLGPILFIMYINDMKQVLKSCEINLFADDTVLFISHKDIKQAESLINFDLNALDGWLRYKKLALNV KKTSYMVMTAGVLDSPPSIVINKEPIERVRQVKYLGVILDDRLKFNTHIDWVIAKVASKCGVISRLAKDL DFFGIVNLYKSLISPHFDFCSSILFLGNKGQIKRLQRLQNRIMRLALGCGRRTSSFVMLDILQWMSVEQR IVYQTMTFIFKLLGGLLPGYLGERIVRGSDVHRHCTRRANEPRVPNLISHGARNSLFFKGIQLYNRLPGE IKNASNLPDFKRRCAAYVKQTV
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Derived: [1] (Consensus) |
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Download Sequence - Format: IG, EMBL, FASTA |
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References: |