Repbase Reports |
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2002, Volume 2, Issue 11 |
November 30, 2002 |
Copyright © 2001-2016 - Genetic Information Research Institute |
ISSN# 1534-830X |
Page 1 |
CR1-1_AG |
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CR1-1_AG is a CR1-like non-LTR retrotransposon - a consensus sequence. |
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Submitted: 00- - 0 |
Accepted: 30-Nov-2002 |
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Key Words: non-LTR retrotransposon; CR1 clade; DNA/RNA-binding; endonuclease; reverse transcriptase; CR1-1_AG |
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Source: Anopheles gambiae str. PEST |
Organism: Anopheles gambiae str. PEST |
Taxonomy: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Anopheles |
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[1] |
Authors: Kapitonov,V.V. and Jurka,J. |
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Title: CR1-1_AG, a family of CR1-like non-LTR retrotransposons from African malaria mosquito. |
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Journal: Repbase Reports 2:(11) p.1 (2002) |
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Abstract: CR1-1_AG is a family of CR1-like non-LTR retrotransposons. The CR1-1_AG consensus sequence was reconstructed based on multiple alignment of ~20 copies identified in the sequenced portion of the genome. Given the ~2% divergence of these copies from the consensus sequence, transposition of CR1-1_AG occurred less than 1 million years ago. Integrations of CR1-1_AG have not produced target site duplications. The consensus sequence encodes two proteins: a 440-aa CR1-1_AG-ORF1p (positions 425 1745) and 941-aa CR1-1_AG-ORF2p (positions 1746-4568). CR1-1_AG_ORF1p is DNA/RNA binding protein composed of the PDH domain (aa positions 3-57) and gag-like zinc knuckle regions (aa positions 334-442). CR1-1_AG-ORF2p is composed the AP endonuclease and reverse transcriptase domains. The 3' terminus is composed of the CAT microsatellite. CR1-1_AG-ORF1p: MECLKCSAVVGTSDDPIICSGSCGFIFHRRCITPTLNKPAVKLINENRNVVYMCDICLDQSAGLVHMDTD ATKSNDLLAQTLRDLEANVSVWISSALERGIETLKTELCAQVERKLETTLRETLSAIEASKMSKAALRAT SDTPQTSKTVQDVNLETWATVTKKRKRTNSGDSNVQTIINRFDEGNNKVTPKIKKINDVKEPMGKNKENN KTLVIVPKVVQSCDRPRADLSARLDPRKQQLSEFRNGRDGQVYAQCPALANLDSIRKEVEDILGDDYSTS LPMARVKIIGMSEKYSSSDLVDLLKSQNEGIPWKQENVIGMFESKIYKYQIHNVVLEIDHETDKCLAKLD KINIGFDRCKISRSIHVMRCFKCGQFSHKSTDCQNKEACSKCSGEHRTSDCTSSILKCVNCVLANTSRNL KLQVQHAANSYECPLFKKQVERRMQLSQ CR1-1_AG-ORF2p: RDECNFLNSRGGVELGRFREILYFNVAGLSSNYAMFRETVEKVQPLLVLISETHVTEKEAFEQFYLKGYR VVSCLSHSRHTGGVAAYARSDVVLKVILNESLEGNWFLGVAVSRGMTVGNYSILYHSPSASDSRFVDILE EWLDRFLDLSKLNIIVGDFNIDWLNVEKSAKLKSLMDSVNMNQKVNEFTRIARQSRTLIDQVYSSIDSIK VTTDPLLKISDHETLVLNINDERCKTIQRKVKCWNRYSKHALCNNVSQGLQCGASDFDEAADLLWNTLKH AMSTLVEEKTIVSRETSRWYTLDLARAKRKRDKVYKKFIRTNRDNDWSEYTKLRNSYSRDLKNRRSDFFS NEINKHKKNSKELWKVLKSMLQPDESCVSVVKFNGVIEADDSIICNKFNSFFVNSVLDINQNIASVSEPS YYVDSATPRCHFRFQKITLEQLKTICFNLTKTAGIGNVSSTTIQDCYHVIGEDLLMVINQSLERGCFPKS WKESLIIPIPKVNGAANAEDFRPINMLHVLEKVLETVVKEQLVQFLNRNELLIREQSGYRQGHSCETALN LVLARWRVLMDRRESIVAVFLDLKRAFETISRPLLLSTLRRFGIVGRELSWFESYLKERTQRTLFGSSVS EPIENTLGVPQGSVLGPILFIMYINDMKQVLKACEINLFADDTVLFISHKEIKQAESLMNIDLNALDGWL KYKKLALNINKTCYMVMSAGVLEEPPSIVINSELIERVRQAKYLGVILDDRLKFHAHIDWVIAKVAKKCG VISRLAKDLDFFGKVHLYKSLISPHFDFCSSILFLGNKGQIKRLQRLQNRIMRLILGCGRRTPSAVMLNI LQWMSVEQRIVYQTMTFIYKMLKGLLPGYLGESIVRGSDIHRHHTRRANEPRVPNLHSQSARNSLFFKGI QRYNSLPDEIKNARNLPDFKRKCVIYVEQTV.
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Derived: [1] (Consensus) |
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Download Sequence - Format: IG, EMBL, FASTA |
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References: |